Biological Therapy for Pyoderma Gangrenosum
نویسندگان
چکیده
منابع مشابه
Adalimumab Therapy for Recalcitrant Pyoderma Gangrenosum
OBJECTIVE To describe a patient with treatment-refractory pyoderma gangrenosum and the outcome of a novel therapeutic approach. METHODS Case report and review of the literature. RESULTS A patient with inflammatory bowel disease developed severe pyoderma gangrenosum while receiving treatment with the chimeric anti-TNF-alpha antibody infliximab. Despite subsequent trials of numerous immunosup...
متن کاملMycophenolate mofetil as therapy for pyoderma gangrenosum.
BACKGROUND Pyoderma gangrenosum is an ulcerative condition that may be associated with inflammatory bowel disease or inflammatory arthritis. In addition to local wound care, management often includes the use of systemic corticosteroids or systemically administered immunomodulatory agents. OBSERVATIONS We retrospectively analyzed 7 patients with pyoderma gangrenosum who were treated with mycop...
متن کاملPyoderma gangrenosum.
Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, noninfective chronic inflammatory skin disorder of unknown etiology. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, haematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violace...
متن کاملNicotine for pyoderma gangrenosum.
A 35-year-old man with no past medical illness developed bloody diarrhea with up to 12 loose stools per day and abdominal pain in February 1984. He had smoked 1 pack of cigarettes per day for 16 years until he stopped smoking 2 months prior to the onset of his illness. In March 1984, he was hospitalized because of toxic dilatation of the colon (toxic megacolon). Treatment consisted of intraveno...
متن کاملPyoderma gangrenosum associated with alitretinoin therapy.
PG: pyoderma gangrenosum INTRODUCTION Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous condition, the etiology of which is poorly understood but is thought to be related to improper neutrophil function and chemotaxis. PG is a clinical diagnosis that requires exclusion of other ulcerative and inflammatory cutaneous disorders. A rare side effect of isotretinoin is the development of ...
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ژورنال
عنوان ژورنال: Journal of Coloproctology
سال: 2013
ISSN: 2237-9363,2317-6423
DOI: 10.1016/j.jcol.2013.08.010